2014年11月20日星期四

How CKD Causes Edema

How does Chronic Kidney Disease (CKD) cause edema? Edema or swelling is one typical symptom appearing in patients with Chronic Kidney Disease (CKD). It usually takes place in patients’ double lower limbs or eyelids especially when they get up in the morning. How does edema or swelling come into being? Edema is a product which is caused by disorder metabolism of water and sodium in the organic body. If the excessive water is more than 10% of the whole body, we call it edema.
The reasons why edema appears are as follows:
Firstly, it is due to the decline of glomerular filtration rate. The reabsorption of renal tubules to water and sodium decreases, which leads to the retention of water and sodium.
Secondly, endocrine hormone can also lead to retention of water and sodium. It is influenced by antidiuretic hormone, aldosterone, etc. When patients are suffering from kidney disease, the secretion of endocrine hormone will be out of balance, which leads to edema or swelling.
Thirdly, edema or swelling can also lead to the decrease of plasma oncotic pressure. In this case, water in the body will move towards tissue space. When patients are suffering from kidney disease, there is usually a large amount of protein which leaks out into urine, which leads to hypoproteinemia. In this case, plasma oncotic pressure will decrease, leading to renal edema.
Fourthly, nephritis is also a factor which can lead to edema or swelling. Nephritis is a kind of immune disease. Immune reaction can also lead to the damage of the whole capillaries. Their permeability can also increase. The water flows to tissues, which leads to edema there.
Different kidney diseases have different degrees of edema as well. For example, acute nephritis can lead to edema. Nephrotic Syndrome can lead to more serious edema. From the above, we can get a conclusion that all renal edema is based on the movement of water to tissues because of the retention of water and sodium.
How to treat renal edema?
As we mentioned in the above, when renal tubules are damaged, the reabsorption of renal tubules will also be influenced. In this case, water will stay in the body, leading to edema. In most of time, diuretic is used. However, it can not repair the damaged renal tubules and treat edema fundamentally. So more and more CKD patients are searching a new method. Micro-Chinese Medicine Osmotherapy can diminish edema from root. The detailed mechanism is as follows:

Firstly, after Micro-Chinese Medicine Osmotherapy enters the body, it will promote blood circulation and dissolve the stasis, which can improve the micro-circulation of the kidney. Secondly, it can clear the stasis, and waste things such as immune complex, which can be out of the body together with urine and reduce the burden of the kidney. Thirdly, after the above steps, the inner environment can be clearer than before. And the nutritious materials can play roles in repairing damaged intrinsic cells by supplying oxygen, etc. Through this, renal tubules can be repaired at the same time. After that, edema will disappear as well.

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